3 – Neil Patrick Harris in ”Harold and Kumar Go to White Castle”
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Neil officially shed his nerdy image (from Doogie Howser) when he stole every scene in Harold & Kumar Go to White Castle. He plays “NPH,” the maniacal, boozing, drug-gobbling, lady-mongering version of himself. This over-the-top lunacy guaranteed his subsequent casting as the womanising Barney Stinson on How I Met Your Mother, one of the most loved and funny characters of American sitcoms.